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Icon for model predictive control for improved product quality - a computer screen with a line graph and the cell culture icon with arrows going between them in a circular fashion

Continuous Cell Culture for Viral Vaccines

ABOUT

Recent events have illustrated the importance of developing new approaches to manufacturing technology for efficiently producing vaccines flexibly and at scale. MIT, together with Merck & Co., Repligen, and the University of Massachusetts Medical School, will use mechanistic modeling to design and construct a continuous vaccine manufacture process. Successful completion of this project will demonstrate the suitability of continuous manufacturing for vaccine production, with potentially transformative effects on supply chains and response times, along with improved product quality attributes. 

FUNDING

  • National Institute for Innovation in Manufacturing Biopharmaceuticals (NIIMBL)  
  • Massachusetts Life Science Center 


RELATED LINKS

  • NIIMBL News
  • NIIMBL Project Description

MIT INVESTIGATORS

Prof. Richard Braatz
(Chemical Engineering)

Prof. Scott Manalis
(Biological Engineering & Koch Institute for Integrative Cancer Research)

Prof. Anthony J. Sinskey
(Biology)

Dr. Stacy L. Springs
(Center for Biomedical Innovation)

PARTNERS

  • Merck & Co. 
  • Repligen 
  • University of Massachusetts Medical School

Learn more about CBI’s research

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About CBI

CBI improves global health through collaboration by bringing together the biomedical industry, government, and academia.

CBI draws on the expertise of the Massachusetts Institute of Technology’s Schools of Engineering and Science, the Sloan School of Management, and the Schwarzman College of Computing.

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