BioMAN Resources

Chen Lab

  • Chen, Q., Khoury, M., Chen, J. (2009) Expression of human cytokine genes dramatically improves reconstitution of specific human blood lineage cells in humanized mice. Proc Natl. Acad. Sci. USA, 106:21783-8. (PDF)

 
Love Lab

  • Song, Q., Han, Q., Bradshaw, E.M., Kent, S.C., Raddassi, K., Nilsson, B., Nepom, G.T., Hafler, D.A. & Love, J.C. On-chip activation and subsequent detection of individual antigen-specific T cells. Anal. Chem. 82, 473–477 (2010). (PDF)
  • Ogunniyi, A.O., Story, C.M., Papa, E., Guillen, E. & Love, J.C. Screening individual hybridomas by microengraving to discover monoclonal antibodies. Nat. Prot. 4, 767-782 (2009) (PDF)
  • Story, C.M., Papa, E., Hu, C.A., Ronan, J.L., Herlihy, K., Ploegh, H.L. & Love, J.C. Profiling antibody responses by multiparametric analysis of single B cells. Proc. Natl. Acad. Sci. U. S. A. 105, 17902-17907 (2008). (PDF)

 
Ram/Sinskey Labs

  • Lee, Harry L. T.,  Paolo Boccazzi, Rajeev J. Ram, et al. Microbioreactor Arrays with Integrated Mixers and Fluid Injectors for High-Throughput Experimentation with pH and Dissolved Oxygen Control. Lab on a Chip, 6: 1229–1235, 2006. (PDF)
  • P. Boccazzi, A. Zanzotto, N. Szita, S. Bhattacharya, K.F. Jensen, A.J. Sinskey. Gene expression analysis of Escherichia coli grown in miniaturized bioreactor platforms for high-thoughput analysis of growth and genomic data. Applied Microbiology and Biotechnology, 68(4):518-32 (2005). (PDF)
  • Z. Zhang, P. Boccazzi, H-G. Choi, G. Perozziello, A. J. Sinskey, K. F. Jensen. Microchemostat—microbial continuous culture in a polymer-based, instrumented microbioreactor. Lab on a Chip 6(7):906-13 (2006). (PDF)
  • P. Boccazzi, Z. Zhang, K. Kurosawa, N. Szita, S. Bhattacharya., K.F. Jensen, A.J. Sinskey. Differential gene expression profiles in Saccharomyces cerevisiae grown in microliter-scale bioreactors equipped with internal stirring and real-time measurements of growth parameters. Biotechnology Progress 22(3):710-16 (2006) (PDF)
  • H.L.T Lee, P. Boccazzi, N. Gorret, R.J. Ram, A.J. Sinskey. In-situ bioprocess monitoring of Escherichia coli bioreactions using Raman spectroscopy. Vibrational Spectroscopy 35(1-2):131-137 (2004) (PDF)
  • A. Zanzotto, N. Szita, P. Boccazzi, Ph. Lessard, A.J. Sinskey, K.F. Jensen. In Situ Measurement of Bioluminescence and Florescence in an Integrated Microbioreactor. Biotechnology and Bioengineering 87(2):243-254 (2004). (PDF)
  • Z. Zhang, G. Perozziello, P. Boccazzi, A.J. Sinskey, O. Geschke, and K.F. Jensen. Microbioreactors for bioprocess development. JALA 12(3): 143-151 (2007). (PDF)
  • K. S. Lee, H. L. T. Lee, R. J. Ram. Optical Multiplexing of Multiple Fluorescence Sensors For Compact, Lab-On-A-Chip Systems. MicroTAS Conference 2007. (PDF)
  • Lee, K. S., Lee, H. L. T., Ram, R. J. Polymer Waveguide Backplanes for Optical Sensor Interfaces in Microfluidics. Lab on a Chip, vol. 7, pp. 1539-1545, 2007. (PDF)

 
Strano Lab

  • Jin, H., Heller, D. et al. Detection of single-molecule H2O2 signaling from epidermal growth factor receptor using fluorescent single-walled carbon nanotubes. Nature Nanotechnology, 2010, in press. (PDF)
  • Kim, J-H, Ahn, J-H et al. A Luciferase/Single-walled Carbon Nanotube Conjugate for Near-Infrared Fluorescent Detection of Cellular ATP. Angewante Chemie, 2010, in press. (PDF)
  • Kim JH, Heller DA, Jin H, Barone PW, Song C, Zhang J, Trudel LJ, Wogan GN, Tannenbaum SR, Strano MS: The rational design of nitric oxide selectivity in single-walled carbon nanotube near-infrared fluorescence sensors for biological detection. Nature Chemistry, 1 (2009) 473-481. (PDF)
  • DA Heller, H Jin, BM Martinez, BM Miller, D Patel, TK Yeung, PV Jena, C Hobartner, TJ Ha, SK Silverman, MS Strano: Multi-modal optical sensing and analyte specificity via single-walled carbon nanotubes. Nature Nanotechnology, 4 (2009) 114-120. (PDF)
  • H Jin, DA Heller, J-H Kim, MS Strano. Stochastic analysis of stepwise fluorescence quenching reactions on single-walled carbon nanotubes: single molecule sensors. Nano Letters, 8 (2008) 4299-304. (PDF)

 
Voldman Lab

  • Kovac, J.R. & Voldman, J. Intuitive, Image-Based Cell Sorting Using Optofluidic Cell Sorting. Analytical Chemistry, 79, 9321-9330 (2007). (PDF)

 
Yanik Lab

  • Rohde C, Angel M, Zeng F, Gonzalez R, Yanik MF. Microfluidic system for on-chip high-throughput whole-animal sorting and screening at subcellular resolution, Proc Natl. Acad. Sci. USA, 104, 13891 (2007). (PDF)
  • Zei F, Rohde C, Yanik MF. Sub-cellular precision on-chip small-animal immobilization, multi-photon imaging and femtosecond-laser manipulation, Lab on a Chip, 8, 653 (2008). Highlighted as HOT Article. (PDF)

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Massachusetts Institute of Technology