Education

Online Course: Principles of Biomanufacturing: Using Biotechnology to Manufacture Medicines

We played a key role in the creation of an online professional education course in the biopharmaceutical manufacturing space to help learners develop an understanding of how a biologic is manufactured and delivered. In the course, MIT faculty and industry experts teach:

  • • How small changes in a protein therapeutic may change its efficacy, safety, and manufacturability.
  • • The method by which living cells are engineered to produce complex therapeutic proteins.
  • • The way in which reactors are designed to support the growth of living cells that produce a target therapeutic.
  • • How protein therapeutics are purified and how previous manufacturing steps inform how this is performed.
  • • The keys to manufacture biopharmaceuticals in a regulated environment and analyze examples and case studies highlighting key biomanufacturing challenges.

 

MIT Instructors: Dr. Paul W. Barone (Center for Biomedical Innovation); Prof. J. Christopher Love (Chemical Engineering); Dr. Stacy Springs (Center for Biomedical Innovation)

Link: https://www.edx.org/course/principles-of-biomanufacturing-using-biotechnology-to-manufacture-medicines

Short Course: Vaccines Bioprocess Development & Commercialization

In collaboration with the UCL MBI Industrial Training Programme, we hold an annual Vaccines Bioprocess Development & Commercialization Workshop.

Each year, this three-day workshop explores the critical issues at the various stages of vaccine development. International experts and instructors from MIT and UCL discuss research, development, operational and regulatory challenges, and opportunities of the vaccine market. The next workshop will be held May 19 – 21, 2020 at UCL.

Link: http://www.ucl.ac.uk/biochemeng/research/mbi/courses/VBDC

Blended Learning for Cell Therapy Manufacturing

In collaboration with Worcester Polytechnic Institute, Celgene, Unum Therapeutics, and Vericel we are creating an online course on the fundamentals of cell therapy manufacturing that is coupled to a companion hands-on training component. Given the clinical successes with cell therapies, such as the recent licensing approvals of CAR T products, there is a growing need for a well-trained workforce to deliver these lifesaving therapies. The development of an online resource that teaches important fundamental concepts, which is also tied to a hands-on training component, will accelerate the training of all levels of the cell therapy manufacturing workforce and decrease the resources required to bring new hires up to speed. Additionally, this type of blended learning environment modernizes learning such that the online component of the training will “immortalize” concepts so that they are available on demand, either to train individuals as they are hired or to review important concepts as needed. Both the online and hands-on courses are expected to launch in the Summer of 2020.

MIT Team: Prof. Krystyn Van Vliet (Biological Engineering, Materials Science & Engineering); Dr. Paul W. Barone (Center for Biomedical Innovation); Elizabeth Skrip (Center for Biomedical Innovation); Dr. Stacy Springs (Center for Biomedical Innovation); Dr. Jacqueline Wolfrum (Center for Biomedical Innovation)
Partners: Celgene, Unum Therapeutics, Vericel, & Worcester Polytechnic Institute
Link: https://niimbl.force.com/s/pc10-007